The Italian actress who has studied theatre appears in her first film, in 1954, in Ettore Scola’s Ridere Ridere Ridere. From 1957, she is cast in several stage plays directed by Michelangelo Antonioni who gives her the leading role of his award winning film, l’Avventura, in 1960s, that imprints her screen persona as a disturbing elegant distant beauty and turns her into an international star. She excels as Antonioni’s muse in such films as Eclipse, in 1962 and Red Desert, in 1964 where he beautifully films the woman who is his lover in real life. For her, he invents the figure of the beautiful intellectual somewhat a little neurotic bourgeois who always seems to feel out of place, to be bored and to hide dozen secrets. Michelangelo Antonioni shows how much her eyes always seem ‘to never stop on an object but to fix, fully absorbed, distant secrets.’ When the relationship between the actress and the director ends, she dares to explore her comedic sense and stars in the decadent and ironic British film, Modest Blaise, in 1966. During the 1970s, she therefore becomes one of the rare grand comedic Italian actresses featured in such productions as the Pizza Triangle, in 1970. From the 1980s, Monica Vitti’s career has declined, only to accept a very little number of performances. Today, the impassible sphinx has Alzheimer and it seems as if her silences and her empty stares on screens had been a tragic prophecy.